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A Case of Lichen Sclerosus et Atrophicus Accompanying Bullous Morphea

机译:伴有大疱性Morphea的地衣菌和萎缩症一例

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摘要

Bullous morphea is a rare form of morphea characterized with bullae on or around atrophic morphea plaques. Whereas lichen sclerosus et atrophicus (LSA) is a disease the etiology of which is not fully known, and which is characterized with sclerosis. Coexistence of morphea and LSA has been identified in some cases. Some authors believe that these two diseases are different manifestations which are on the same spectrum. The 70-year-old patient stated herein, presented to us for 6 months with annular, atrophic plaques, ivory color in the middle, surrounded by living erythema, on the front and back of the trunk. Occasionally bulla formation on the plaques on the trunk lateral was identified. Fibrotic and atrophic plaques of ligneous hardness were present on the front side of tibia of both legs. In the histopathologic examination, the lesions were found concordant with bullous morphea and LSA. With colchicine 1.5 mg/day, pentoxifylline 1,200 mg/day, topical calcipotriol ointment and clobetasol propionate cream, the erythema in the patient's lesions faded and softening in the fibrotic plaques was observed. Concomitance of bullous morphea and LSA is a rarely seen, interesting coexistence which suggests a common, as yet unknown, underlying pathogenesis.
机译:大疱性吗啡是一种罕见的吗啡形态,其特征在于萎缩性吗啡斑上或周围的大疱。地衣性硬化症和萎缩性贫血(LSA)是一种病因,其病因尚不完全清楚,其特征是硬化。在某些情况下,已经确定了吗啡和LSA并存。一些作者认为,这两种疾病是在同一频谱上的不同表现。本文所述的一名70岁患者在躯干的前部和后部向我们展示了6个月的环状,萎缩性斑块,中间呈象牙色,周围有活的红斑。偶尔会在躯干外侧斑块上发现大疱。木质硬度的纤维化和萎缩斑块出现在双腿胫骨的前侧。在组织病理学检查中,发现病灶与大疱性吗啡和LSA相一致。使用秋水仙碱1.5 mg /天,己酮可可碱1200 mg /天,局部卡泊三醇软膏和氯倍他索丙酸酯乳膏,观察到患者病变中的红斑消退并在纤维化斑块中软化。大疱性吗啡与LSA的并存是一种罕见的有趣的共存,提示常见的,但尚未发现的潜在发病机理。

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