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The epidemic of SIDS in Norway 1967-93: changing effects of riskfactors

机译:1967-93年挪威小岛屿发展中国家的流行:风险影响的变化因素

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摘要

Accepted 18 March 1997
Time trends on the association of maternal age, birth order, and marital status with the risk of sudden infant death syndrome (SIDS) and non-SIDS deaths in Norway were analysed: 2356 postperinatal SIDS deaths and 4069 postperinatal non-SIDS deaths were ascertained during 1967-93. The SIDS incidence was 1.25 per 1000 in 1967,reached a peak of 2.69 in 1988, and fell to 1.22 in 1990 after the initiation of an intervention programme to avoid prone sleeping. In the entire period, young maternal age, high birth order, and unmarried motherhood were associated with SIDS. The adverse effects of young maternal age and high birth order increased continuously with time. From 1967-71 to 1990-93, the relative risk for maternal age < 20 years v maternal age 25-29 changed from 2.5 (95% confidence interval 2.0 to 3.2) to 7.0 (95% CI 4.2 to 11.9) (p < 0.0001), and for birth order 4+ v birth order 1 from 3.2 (95% CI 2.5 to 4.2) to 14.4 (95% CI 8.3 to 24.9) (p < 0.0001). Effects on non-SIDS deaths were far weaker and no secular trends were observed. The strong association of young maternal age, high birth order, and marital status in SIDS, but not in non-SIDS, provides evidence thatSIDS is an epidemiological entity. The increasing effects of youngmaternal age and high birth order, which continued after the suddendrop in the SIDS rate in 1990, suggest that further efforts to preventSIDS should be aimed particularly at identifying causal mechanisms inhigh risk groups.

机译:1997年3月18日被接受
分析了挪威的产妇年龄,出生顺序和婚姻状况与婴儿猝死综合症(SIDS)和非SIDS死亡风险的关联的时间趋势:围产期SIDS死亡2356例和4069例1967-93年期间确定了围产期非SIDS死亡。 1967年,小岛屿发展中国家的发病率是每千人1.25例,在1988年达到2.69的峰值,并在采取干预措施以避免俯卧睡眠后于1990年下降到1.22。在整个时期中,年轻的母亲年龄,高的生育顺序和未婚的母亲与小岛屿发展中国家有关。年轻的母亲年龄和较高的出生顺序的不利影响随着时间的推移不断增加。从1967-71年到1990-93年,产妇年龄<20岁相对于25-29岁母亲的相对风险从2.5(95%置信区间2.0到3.2)变为7.0(95%CI 4.2到11.9)(p <0.0001 ),并且对于出生顺序4+ v出生顺序1从3.2(95%CI 2.5至4.2)到14.4(95%CI 8.3至24.9)(p <0.0001)。对非小岛屿发展中国家死亡的影响要弱得多,没有观察到长期趋势。小岛屿发展中国家而非非小岛屿发展中国家的年轻孕产妇年龄,高出生顺序和婚姻状况之间的密切联系提供了以下证据:小岛屿发展中国家是一种流行病学实体。年轻的影响越来越大产妇年龄和高出生顺序,在突然之间持续1990年小岛屿发展中国家的比率下降,表明需要进一步努力防止小岛屿发展中国家特别应着眼于确定高危人群。

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