A Polymorphism Located Near PMAIP1/Noxa Gene Influences Susceptibility to Hodgkin Lymphoma Development in South India

机译：位于PMAIP1 / Noxa基因附近的多态性影响印度南部霍奇金淋巴瘤发展的易感性

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Background:Single nucleotide polymorphisms (SNPs) in DNA repair and Toll-like receptor (TLR) genes have been reported to be associated with Hodgkin Lymphoma (HL) risk. Since such associations may be ethnicity dependent, polymorphisms in TLR4 rs1554973, Xeroderma pigmentosum C (XPC) rs2228000, rs2228001 and a variant near PMAIP1/Noxa gene rs8093763 were here investigated with regard to HL susceptibility in a south Indian population. Normative frequencies of SNPs were established and compared with data for 1000 genome populations.

机译：背景：DNA修复和Toll样受体（TLR）基因中的单核苷酸多态性（SNP）已被报道与霍奇金淋巴瘤（HL）风险相关。由于此类关联可能是种族依赖性的，因此本文针对南印度人的HL易感性，研究了TLR4 rs1554973，色素干性皮肤干燥性紫癜（XPC）rs2228000，rs2228001和PMAIP1 / Noxa基因rs8093763附近的变异。建立了SNPs的标准频率，并与1000个基因组种群的数据进行了比较。

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期刊名称 Asian Pacific Journal of Cancer Prevention : APJCP
作者
Dimpal N Thakkar; Sunitha Kodidela; Selvarajan Sandhiya; Biswajit Dubashi; Steven Aibor Dkhar;
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作者单位

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年(卷),期 2017(18),9
年度 2017
页码 2477–2483
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Hodgkin lymphoma polymorphisms DNA Repair PMAIP1/Noxa TLR4;

机译：霍奇金淋巴瘤;多态性;DNA修复;PMAIP1 / Noxa;TLR4;

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专利

1. A Polymorphism Located Near PMAIP1/Noxa Gene Influences Susceptibility to Hodgkin Lymphoma Development in South India [J] . Dimpal N Thakkar, Sunitha Kodidela, Sandhiya Selvarajan, Asian Pacific Journal of Cancer Prevention . 2017,第9期

机译：位于PMAIP1 / Noxa基因附近的多态性影响印度南部霍奇金淋巴瘤发展的易感性
2. Frequency distribution of BLMH, XPO5 and HFE gene polymorphisms in the South Indian population and their association with Hodgkin Lymphoma [J] . Dimpal N. Thakkar, Sreenivasulu Palugulla, Sandhiya Selvarajan, The International journal of biological markers . 2018,第4期

机译：南印度人口中BLMH，XPO5和HFE基因多态性的频率分布及其与霍奇金淋巴瘤的关系
3. Frequency distribution of BLMH, XPO5 and HFE gene polymorphisms in the South Indian population and their association with Hodgkin Lymphoma [J] . Thakkar Dimpal N., Palugulla Sreenivasulu, Selvarajan Sandhiya, The International journal of biological markers . 2018,第4期

机译：南印度人群BLMH，XPO5和HFE基因多态性的频率分布及其与霍奇金淋巴瘤的关联
4. Development of Single Domain Antibodies for Diagnosis and Treatment of Naturally Occurring Canine Lymphoma: An Animal Model for Human Non-Hodgkin Lymphoma [C] . Joana Dias, Solange Gil, Belmira Carrapico, PEGS . 2015

机译：天然犬淋巴瘤诊断和治疗单结构域抗体的发展：人非霍奇金淋巴瘤的动物模型
5. Hepatitis B and C infections, single nucleotide polymorphisms of the inflammatory pathway, and the risk of non-Hodgkin's lymphoma. [D] . Ng, Leslie J. 2008

机译：乙型和丙型肝炎感染，炎性途径的单核苷酸多态性以及非霍奇金淋巴瘤的风险。
6. Discrepant NOXA (PMAIP1) transcript and NOXA protein levels: a potential Achilles heel in mantle cell lymphoma [O] . M A Dengler, A Weilbacher, M Gutekunst, 2014

机译：不一致的NOXA（PMAIP1）转录本和NOXA蛋白水平：套细胞淋巴瘤的潜在致命弱点
7. Frequency distribution of BLMH, XPO5 and HFE gene polymorphisms in the South Indian population and their association with Hodgkin Lymphoma [O] . Dimpal N. Thakkar, Sreenivasulu Palugulla, Sandhiya Selvarajan, 2018

机译：南印度人群BLMH，XPO5和HFE基因多态性的频率分布及其与霍奇金淋巴瘤的关联

A Polymorphism Located Near PMAIP1/Noxa Gene Influences Susceptibility to Hodgkin Lymphoma Development in South India

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