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Optimization of Swine Breeding Programs Using Genomic Selection with ZPLAN+

机译:使用ZPLAN +进行基因组选择优化猪育种程序

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摘要

The objective of this study was to evaluate the present conventional selection program of a swine nucleus farm and compare it with a new selection strategy employing genomic enhanced breeding value (GEBV) as the selection criteria. The ZPLAN+ software was employed to calculate and compare the genetic gain, total cost, return and profit of each selection strategy. The first strategy reflected the current conventional breeding program, which was a progeny test system (CS). The second strategy was a selection scheme based strictly on genomic information (GS1). The third scenario was the same as GS1, but the selection by GEBV was further supplemented by the performance test (GS2). The last scenario was a mixture of genomic information and progeny tests (GS3). The results showed that the accuracy of the selection index of young boars of GS1 was 26% higher than that of CS. On the other hand, both GS2 and GS3 gave 31% higher accuracy than CS for young boars. The annual monetary genetic gain of GS1, GS2 and GS3 was 10%, 12%, and 11% higher, respectively, than that of CS. As expected, the discounted costs of genomic selection strategies were higher than those of CS. The costs of GS1, GS2 and GS3 were 35%, 73%, and 89% higher than those of CS, respectively, assuming a genotyping cost of $120. As a result, the discounted profit per animal of GS1 and GS2 was 8% and 2% higher, respectively, than that of CS while GS3 was 6% lower. Comparison among genomic breeding scenarios revealed that GS1 was more profitable than GS2 and GS3. The genomic selection schemes, especially GS1 and GS2, were clearly superior to the conventional scheme in terms of monetary genetic gain and profit.
机译:这项研究的目的是评估当前的猪核农场常规选择方案,并将其与采用基因组增强育种值(GEBV)作为选择标准的新选择策略进行比较。使用ZPLAN +软件计算和比较每种选择策略的遗传增益,总成本,回报和利润。第一个策略反映了当前的常规育种程序,即后代测试系统(CS)。第二种策略是严格基于基因组信息(GS1)的选择方案。第三种情况与GS1相同,但是性能测试(GS2)进一步补充了GEBV的选择。最后一种情况是基因组信息和后代测试(GS3)的混合。结果表明,GS1幼猪选择指数的准确性比CS高26%。另一方面,GS2和GS3的公猪准确性均比CS高31%。 GS1,GS2和GS3的年货币遗传收益分别比CS高10%,12%和11%。不出所料,基因组选择策略的折现成本高于CS。假设基因分型成本为$ 120,GS1,GS2和GS3的成本分别比CS的成本高35%,73%和89%。结果,GS1和GS2的每只动物的折现利润分别比CS高8%和2%,而GS3的低折现利润。基因组育种方案之间的比较表明,GS1比GS2和GS3更有利可图。基因组选择方案,特别是GS1和GS2,在货币遗传收益和利润方面明显优于常规方案。

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