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Upregulation of MiR-196a promotes cell proliferation by downregulating p27kip1 in laryngeal cancer

机译：MiR-196a的上调通过下调喉癌中的p27kip1促进细胞增殖

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摘要

BackgroundAccumulating evidence has confirmed that miR-196a plays a critical role in tumorigenesis and tumor progression in a variety of cancers. It has been demonstrated that miR-196a is highly up-regulated in laryngeal cancer by miRNA profiling analysis. However, the functional mechanism of miR-196a in laryngeal cancer remains unclear. This study aims to explore the mechanism of miR-196a in laryngeal cancer.

机译：背景越来越多的证据证实，miR-196a在多种癌症的肿瘤发生和肿瘤进展中起着关键作用。通过miRNA谱分析已证明miR-196a在喉癌中高度上调。但是，miR-196a在喉癌中的功能机制仍不清楚。本研究旨在探讨miR-196a在喉癌中的作用机制。

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期刊名称 Biological Research
作者
Cheng Jin; Yi Zhang; Jiping Li;
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作者单位

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年(卷),期 2016(49),-1
年度 2016
页码 40
总页数 8
原文格式 PDF
正文语种
中图分类生物学;
关键词
miR-196a p27supkip1/sup Laryngeal cancer;

机译：miR-196a;p27 sup kip1 / sup;喉癌;

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专利

1. Upregulation of MiR-196a promotes cell proliferation by downregulating p27 kip1 in laryngeal cancer [J] . Cheng Jin, Yi Zhang, Jiping Li Biological research: BR . 2016,第1期

机译：MiR-196a的上调通过下调喉癌中的p27 kip1促进细胞增殖
2. MiR-196a Is Upregulated in Gastric Cancer and Promotes Cell Proliferation by Downregulating p27kip1. [J] . Ming Sun, Xiang-Hua Liu, Jin-Hai Li, Molecular cancer therapeutics . 2012,第4期

机译：MiR-196a在胃癌中上调，并通过下调p27kip1促进细胞增殖。
3. miR-222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27kip1 [J] . SunC., LiN., ZhouB., Oncology letters . 2013,第2期

机译：miR-222在上皮性卵巢癌中上调，并通过下调P27kip1促进细胞增殖
4. Ang-2 promoting proliferation of SW1116 colon cancer cells through PI3K/Akt pathways [C] . Hong Zhang Ji, Yang Wen Chun, Ping Wang Ai, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：Ang-2通过PI3K / Akt途径促进SW1116结肠癌细胞的增殖
5. DLX4 homeoprotein promotes PI3K/Akt anti-apoptosis pathway in ER negative breast cancer cells through upregulation of VEGFA. [D] . Wu, Weiwei. 2010

机译：DLX4同源蛋白通过上调VEGFA促进ER阴性乳腺癌细胞中的PI3K / Akt抗凋亡途径。
6. miR-222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27kip1 [O] . CHAOYANG SUN, NA LI, BO ZHOU, -1

机译：miR-222在上皮性卵巢癌中上调并通过下调P27kip1促进细胞增殖
7. Upregulation of MiR-196a promotes cell proliferation by downregulating p27kip1 in laryngeal cancer [O] . Cheng Jin, Yi Zhang, Jiping Li 2016

机译：MiR-196a的上调通过下调喉癌中的p27kip1促进细胞增殖

Upregulation of MiR-196a promotes cell proliferation by downregulating p27kip1 in laryngeal cancer

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