In vivo degradation and neovascularization of silk fibroin implants monitored by multiple modes ultrasound for surgical applications

摘要

BackgroundIn this paper we aimed to investigate the neovascularization and biodegradation of the silk fibroin in vivo using multiple modes ultrasound, including two-dimensional, three-dimensional and contrast-enhanced ultrasound by quantifying the echo intensity, volume and contrast enhancement of the silk fibroin implants.