Prediction of the mechanical response of cardiac alternans by using an electromechanical model of human ventricular myocytes

摘要

PurposeAlthough the quantitative analysis of electromechanical alternans is important, previous studies have focused on electrical alternans, and there is a lack quantitative analysis of mechanical alternans at the subcellular level according to various basic cycle lengths (BCLs). Therefore, we used the excitation–contraction (E–C) coupling model of human ventricular cells to quantitatively analyze the mechanical alternans of ventricular cells according to various BCLs.