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AutoAssemblyD: a graphical user interface system for several genome assemblers

机译:AutoAssemblyD:用于多个基因组组装者的图形用户界面系统

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摘要

Next-generation sequencing technologies have increased the amount of biological data generated. Thus, bioinformatics has become important because new methods and algorithms are necessary to manipulate and process such data. However, certain challenges have emerged, such as genome assembly using short reads and high-throughput platforms. In this context, several algorithms have been developed, such as Velvet, Abyss, Euler-SR, Mira, Edna, Maq, SHRiMP, Newbler, ALLPATHS, Bowtie and BWA. However, most such assemblers do not have a graphical interface, which makes their use difficult for users without computing experience given the complexity of the assembler syntax. Thus, to make the operation of such assemblers accessible to users without a computing background, we developed AutoAssemblyD, which is a graphical tool for genome assembly submission and remote management by multiple assemblers through XML templates.AvailabilityAssemblyD is freely available at It requires Sun jdk 6 or higher.
机译:下一代测序技术已增加了生成的生物学数据的数量。因此,生物信息学已经变得很重要,因为必须要有新的方法和算法来处理和处理这些数据。但是,出现了一些挑战,例如使用短读和高通量平台进行基因组组装。在这种情况下,已经开发了几种算法,例如Velvet,Abyss,Euler-SR,Mira,Edna,Maq,SHRiMP,Newbler,ALLPATHS,Bowtie和BWA。但是,大多数这样的汇编器没有图形界面,考虑到汇编器语法的复杂性,如果没有计算经验,这会使用户难以使用它们。因此,为了使没有计算机背景的用户可以访问此类汇编器的操作,我们开发了AutoAssemblyD,这是一种图形工具,用于通过XML模板由多个汇编器提交基因组组装并进行远程管理。或更高。

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