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Biocompatible synthesis of reduced graphene oxide from Euphorbia heterophylla (L.) and their in-vitro cytotoxicity against human cancer cell lines

机译:大戟(L.)的生物相容性还原氧化石墨烯的合成及其对人癌细胞系的体外细胞毒性

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摘要

class="kwd-title">Keywords: Euphorbia heterophylla (L.), Reduced graphene oxide (rGO), X-ray diffraction, Cytotoxicity class="head no_bottom_margin" id="abs0015title">AbstractFacile and biocompatible synthesis of reduced graphene oxide from graphene oxide as a precursor and aqueous leaves extract of Euphorbia heterophylla (L.), act as a reducing /capping /stabilizing agent by green chemistry approaches. The obtained product was analyzed by Ultraviolet-Visible spectroscopy (UV–vis), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy and Scanning electron Microscopy (SEM). In addition to this, the significant cytotoxicity of rGO studied against cancerous cell lines such as A549- Human Lung cancer cell line and HepG2-Human Hepatocarcinoma Cell lines in-vitro. These results indicate that the biocompatible synthesis of rGO is straightforward, inexpensive and environmentally friendly for promising large-scale production of industrial purpose and then finding further biomedical applications.
机译:<!-fig ft0-> <!-fig @ position =“ anchor” mode =文章f4-> <!-fig mode =“ anchred” f5-> <!-fig / graphic | fig / alternatives / graphic mode =“ anchored” m1-> class =“ kwd-title”>关键字:大叶大戟(L.),氧化石墨烯(rGO),X射线衍射,细胞毒性< h2 class =“ head no_bottom_margin” id =“ abs0015title”>摘要以大戟大戟(L.)的前体和水性叶片提取物为原料,以生物兼容的方式合成还原的氧化石墨烯,具有还原/加帽作用/稳定剂通过绿色化学方法。通过紫外可见光谱(UV-vis),X射线衍射(XRD),傅里叶变换红外光谱(FT-IR),拉曼光谱和扫描电子显微镜(SEM)对所得产物进行分析。除此之外,还研究了rGO对癌细胞系(如A549-人肺癌细胞系和HepG2-人肝癌细胞系)的显着细胞毒性。这些结果表明,rGO的生物相容性合成简单,廉价且对环境友好,可实现工业目的的大规模生产,然后找到进一步的生物医学应用。

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