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GeneSCF: a real-time based functional enrichment tool with support for multiple organisms

机译:GeneSCF:基于实时的功能丰富工具支持多种生物

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摘要

BackgroundHigh-throughput technologies such as ChIP-sequencing, RNA-sequencing, DNA sequencing and quantitative metabolomics generate a huge volume of data. Researchers often rely on functional enrichment tools to interpret the biological significance of the affected genes from these high-throughput studies. However, currently available functional enrichment tools need to be updated frequently to adapt to new entries from the functional database repositories. Hence there is a need for a simplified tool that can perform functional enrichment analysis by using updated information directly from the source databases such as KEGG, Reactome or Gene Ontology etc.
机译:背景技术ChIP测序,RNA测序,DNA测序和定量代谢组学等高通量技术可产生大量数据。研究人员通常依靠功能富集工具从这些高通量研究中解释受影响基因的生物学意义。但是,当前可用的功能丰富工具需要经常更新以适应功能数据库存储库中的新条目。因此,需要一种简化的工具,该工具可以通过直接使用诸如KEGG,Reactome或Gene Ontology等源数据库中的更新信息来执行功能丰富性分析。

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