Gene expression profiling of Naïve sheep genetically resistant and susceptible to gastrointestinal nematodes

摘要

BackgroundGastrointestinal nematodes constitute a major cause of morbidity and mortality in grazing ruminants. Individual animals or breeds, however, are known to differ in their resistance to infection. Gene expression profiling allows us to examine large numbers of transcripts simultaneously in order to identify those transcripts that contribute to an animal's susceptibility or resistance.