Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection

摘要

BackgroundCell-surface mucins are expressed in apical epithelial cells of the respiratory tract, and contribute a crucial part of the innate immune system. Despite anti-inflammatory or antiviral functions being revealed for certain cell-surface mucins such as MUC1, the roles of other mucins are still poorly understood, especially in viral infections.