Microarray of surface-exposed proteins of rickettsia heilongjiangensis for serodiagnosis of Far-eastern spotted fever

摘要

BackgroundFar-eastern spotted fever (FESF) is an important emerging infectious disease in Northeast Asia. The laboratory diagnosis of FESF in hospitals is mainly based on serological methods. However, these methods need to cultivate rickettsial cells as diagnostic antigens, which is both burdensome and dangerous.