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The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data

机译：剂量策略对青蒿琥酯-阿莫地喹治疗非复杂性疟疾疗效的影响：单个患者数据的荟萃分析

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摘要

BackgroundArtesunate-amodiaquine (AS-AQ) is one of the most widely used artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium falciparum malaria in Africa. We investigated the impact of different dosing strategies on the efficacy of this combination for the treatment of falciparum malaria.

机译：背景青蒿琥酯-氨二喹（AS-AQ）是治疗非洲单纯性恶性疟原虫疟疾的最广泛使用的基于青蒿素的联合疗法（ACT）之一。我们调查了不同剂量策略对这种组合治疗恶性疟疾疗效的影响。

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期刊名称 BMC Medicine
作者

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年(卷),期 2015(13),-1
年度 2015
页码 66
总页数 19
原文格式 PDF
正文语种
中图分类基础医学;
关键词
Malaria Plasmodium falciparum Drug resistance Artesunate Amodiaquine Dosing Efficacy;

机译：疟疾;恶性疟原虫;药物耐药性;青蒿琥酯;阿莫地喹;给药;功效;

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专利

1. The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data [J] . BMC Medicine . 2015,第1期

机译：剂量策略对青蒿琥酯-阿莫地喹治疗非复杂性疟疾疗效的影响：单个患者数据的荟萃分析
2. Therapeutic efficacy and effects of artemether-lumefantrine and artesunate-amodiaquine coformulated or copackaged on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in Southwest Nigeria. [J] . Gbotosho GO, Sowunmi A, Okuboyejo TM, The American Journal of Tropical Medicine and Hygiene . 2011,第5期

机译：尼日利亚西南部单纯性恶性疟原虫疟疾儿童联合配制或联合包装的蒿甲醚-卢美他汀和青蒿琥酯-阿莫地喹对疟疾相关贫血的治疗效果和作用。
3. Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: a systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data [J] . WorldWide Antimalarial Resistance Network (WWARN) Lumefantrine PK/PD Study Group BMC Medicine . 2015,第1期

机译：蒿甲醚-黄麻黄素治疗单纯性恶性疟原虫疟疾：第7天使用单独患者数据对黄麻黄素浓度和治疗反应的系统评价和荟萃分析
4. A Bayesian Review of the Meta-Analysis on the Efficacy of Bone Marrow-Derived Cells Transplantation in Adult Patients with Heart Diseases [C] . Siew-Pang Chan, Rosalind Lee, Kim-Leng Poh World Congress on Engineering . 2009

机译：贝叶斯审查骨髓源细胞移植在成人患者心脏病患者中的疗效综述
5. New therapeutics for cerebral malaria: An investigation into the effect of HMG-CoA reductase inhibitors and anti-apoptotic strategies in experimental cerebral malaria. [D] . Helmers, Andrew. 2008

机译：脑部疟疾的新疗法：HMG-CoA还原酶抑制剂的作用和抗凋亡策略在实验性脑部疟疾中的研究。
6. Therapeutic Efficacy and Effects of Artemether-Lumefantrine and Artesunate-Amodiaquine Coformulated or Copackaged on Malaria-Associated Anemia in Children with Uncomplicated Plasmodium falciparum Malaria in Southwest Nigeria [O] . Grace O. Gbotosho, Akintunde Sowunmi, Titilope M. Okuboyejo, 2011

机译：尼日利亚西南部单纯性恶性疟原虫疟疾儿童联合配制或联合包装的蒿甲醚-卢美芬汀和青蒿琥酯-阿莫地喹对疟疾相关贫血的治疗效果及疗效
7. The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data [O] . Adjuik, MA, Allan, R, Anvikar, AR, 2015

机译：剂量策略对青蒿琥酯-阿莫地喹治疗非复杂性疟疾疗效的影响：单个患者数据的荟萃分析

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data

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