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Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility

机译：错配修复基因的常见变异与精子DNA损伤和男性不育的风险增加有关

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摘要

BackgroundThe mismatch repair (MMR) pathway plays an important role in the maintenance of the genome integrity, meiotic recombination and gametogenesis. This study investigated whether genetic variations in MMR genes are associated with an increased risk of sperm DNA damage and male infertility.

机译：背景错配修复（MMR）途径在维持基因组完整性，减数分裂重组和配子发生中起重要作用。这项研究调查了MMR基因的遗传变异是否与精子DNA损伤和男性不育的风险增加有关。

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期刊名称 BMC Medicine
作者
Guixiang Ji; Yan Long; Yong Zhou; Cong Huang; Aihua Gu; Xinru Wang;
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作者单位

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年(卷),期 2012(10),-1
年度 2012
页码 49
总页数 10
原文格式 PDF
正文语种
中图分类基础医学;
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专利

1. Re: Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility [J] . NiederbergerC. The Journal of Urology . 2013,第1期

机译：回复：错配修复基因的常见变异与精子DNA损伤和男性不育的风险增加相关
2. Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility [J] . Guixiang Ji, Yan Long, Yong Zhou, BMC Medicine . 2012,第1期

机译：错配修复基因的常见变异与精子DNA损伤和男性不育的风险增加相关
3. Genetic variants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population [J] . JiG., GuA., WangY., Free Radical Biology and Medicine: The Official Journal of the Oxygen Society . 2012,第4期

机译：抗氧化剂基因的遗传变异与中国人口的精子DNA损伤和男性不育风险相关
4. The associations of sequence variants in DNA-repair and cell-cycle genes with cancer risk: genotype-phenotype correlations [C] . Janet Hall, Virginie Marcel, Celeste Bolin Biochemical Society Symposium . 2009

机译：DNA修复和细胞周期基因中序列变体在具有癌症风险的关联：基因型 - 表型相关性
5. Molecular genetic analysis of the flagellar axoneme and fibrous sheath in sperm motility and male infertility. [D] . Turner, Regina Marie Oristaglio. 1999

机译：鞭毛轴突和纤维鞘在精子运动和男性不育中的分子遗传学分析。
6. Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers? [O] . Aung Ko Win, John L. Hopper, Daniel D. Buchanan, -1

机译：是与DNA错配修复基因突变载体的结直肠癌风险相关的常见遗传变体？
7. Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility [O] . Guixiang Ji, Yan Long, Yong Zhou, 2012

机译：错配修复基因的常见变异与精子DNA损伤和男性不育的风险增加有关

Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility

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