Diabetic nephropathy in a sibling and albuminuria predict early GFR decline: a prospective cohort study

摘要

BackgroundDiabetic nephropathy is a growing clinical problem, and the cause for >40% of incident ESRD cases. Unfortunately, few modifiable risk factors are known. The objective is to examine if albuminuria and history of diabetic nephropathy (DN) in a sibling are associated with early DN progression or mortality.