Sarcomere length-dependence of activity-dependent twitch potentiation in mouse skeletal muscle

摘要

BackgroundIt has been reported that potentiation of a skeletal muscle twitch response is proportional to muscle length with a negative slope during staircase, and a positive slope during posttetanic potentiation. This study was done to directly compare staircase and posttetanic responses with measurement of sarcomere length to compare their length-dependence.