Volume loading augments cutaneous vasodilatation and cardiac output of heat stressed older adults

摘要

Key points class="unordered" style="list-style-type:disc" id="tjp12569-list-0001">Age‐related changes in cutaneous microvascular and cardiac functions limit the extent of cutaneous vasodilatation and the increase in cardiac output that healthy older adults can achieve during passive heat stress.However, it is unclear if these age‐related changes in microvascular and cardiac functions maximally restrain the levels of cutaneous vasodilatation and cardiac output that healthy older adults can achieve during heat stress.We observed that rapid volume loading, performed during passive heat stress, augments both cutaneous vasodilatation and cardiac output in healthy older humans.These findings demonstrate that the microcirculation of healthy aged skin can further dilate during passive heat exposure, despite peripheral limitations to vasodilatation.Furthermore, healthy older humans can augment cardiac output when cardiac pre‐load is increased during heat stress.