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Population structure and history of the Welsh sheep breeds determined by whole genome genotyping

机译:全基因组基因分型确定威尔士绵羊品种的种群结构和历史

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摘要

BackgroundOne of the most economically important areas within the Welsh agricultural sector is sheep farming, contributing around £230 million to the UK economy annually. Phenotypic selection over several centuries has generated a number of native sheep breeds, which are presumably adapted to the diverse and challenging landscape of Wales. Little is known about the history, genetic diversity and relationships of these breeds with other European breeds. We genotyped 353 individuals from 18 native Welsh sheep breeds using the Illumina OvineSNP50 array and characterised the genetic structure of these breeds. Our genotyping data were then combined with, and compared to, those from a set of 74 worldwide breeds, previously collected during the International Sheep Genome Consortium HapMap project.
机译:背景威尔士农业领域中最重要的经济领域之一是养羊业,每年为英国经济贡献约2.3亿英镑。经过几个世纪的表型选择,已经产生了许多本地绵羊品种,这些品种可能适应了威尔士多样化而富挑战性的景观。关于这些品种的历史,遗传多样性以及与其他欧洲品种的关系知之甚少。我们使用Illumina OvineSNP50阵列对来自18个威尔士本地绵羊品种的353个个体进行了基因分型,并表征了这些品种的遗传结构。然后,将我们的基因分型数据与先前在国际绵羊基因组联盟HapMap项目中收集的74种全球品种的基因型数据进行了组合和比较。

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