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美国卫生研究院文献>BMJ Case Reports
>Unusual presentation of more common disease/injury: Atypical transformation in sacral drop metastasis from posterior fossa choroid plexus papilloma
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Unusual presentation of more common disease/injury: Atypical transformation in sacral drop metastasis from posterior fossa choroid plexus papilloma
Choroid plexus papillomas (CPP) are rare tumours and spinal metastases of CPP are even less common. We report a 50-year-old woman with spinal drop metastases at Th9 and S1–2 6 years after total resection of a posterior fossa CPP. The metastasis at S1–2 was resected and histological examination showed transformation to an atypical CPP. Atypical transformation in a metastasis years after resection of a benign posterior fossa CPP has been described once. We would like to advocate craniospinal MRI at the time of initial diagnosis as well as periodic follow-up after total and subtotal resection of a posterior fossa CPP in adults at least once in 1 or 2 years, depending on the histological grading of the primary CPP. In our case report, this could have resulted in earlier diagnosis of the locoregional recurrence or of the spinal drop metastasis.
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