TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast

摘要

Background: Phyllodes tumors are rare fibroepithelial neoplasms of the breast, which carry the potential risk of local recurrence and metastasis. Phyllodes tumors share several histological features with fibroadenomas, and no widely accepted markers for distinguishing these lesions have been identified.