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Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity

机译：血清CXCL16升高是卵巢癌存活率低的独立预测因子可能反映了转移前ADAM蛋白酶的活性

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摘要

Background: In certain cancers, expression of CXCL16 and its receptor CXCR6 associate with lymphocyte infiltration, possibly aiding anti-tumour immune response. In other cancers, CXCL16 and CXCR6 associate with pro-metastatic activity. In the current study, we aimed to characterise the role of CXCL16, sCXCL16, and CXCR6 in ovarian cancer (OC).

机译：背景：在某些癌症中，CXCL16及其受体CXCR6的表达与淋巴细胞浸润相关，可能有助于抗肿瘤免疫反应。在其他癌症中，CXCL16和CXCR6与转移活性有关。在当前的研究中，我们旨在表征CXCL16，sCXCL16和CXCR6在卵巢癌（OC）中的作用。

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期刊名称 British Journal of Cancer
作者
M J M Gooden; V R Wiersma; A Boerma; N Leffers; H M Boezen; K A ten Hoor; H Hollema; A M E Walenkamp; T Daemen; H W Nijman; E Bremer;
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作者单位

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年(卷),期 2014(110),6
年度 2014
页码 1535–1544
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
CXCL16 CXCR6 ADAMs ovarian cancer prognosis;

机译：CXCL16;CXCR6;ADAM;卵巢癌;预后;
入库时间 2022-08-17 13:52:21

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2. Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity [J] . M J M Gooden, V R Wiersma, A Boerma, British Journal of Cancer . 2014,第6期

机译：血清CXCL16升高是卵巢癌存活率低的独立预测因子，可能反映了转移前ADAM蛋白酶的活性
3. Elevated serum HER‐2 predicts poor prognosis in breast cancer and is correlated to ADAM10 expression [J] . Hui Zheng, Ailing Zhong, Suhong Xie, Cancer Medicine . 2019,第2期

机译：血清HER-2升高可预测乳腺癌的预后不良，并且与ADAM10表达相关
4. Elevated perioperative serum CA 19-9 levels are independent predictors of poor survival in patients with resectable cholangiocarcinoma [J] . KondoN., MurakamiY., UemuraK., Journal of Surgical Oncology . 2014,第4期

机译：围手术期血清CA 19-9水平升高是可切除胆管癌患者生存不良的独立预测因素
5. Computer extracted features related to the spatialarrangement of tumor-infiltrating lymphocytes predict overall survival in epithelial ovarian cancer receiving adjuvant chemotherapy [C] . Sepideh Azarianpour, Germán Corredor, Kaustav Bera, Conference on Medical Imaging: Digital Pathology . 2020

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6. Hormone therapy and physical activity as predictors of lung cancer risk and survival: The California Teachers Study. [D] . DeHart, Jessica Noelle Clague. 2010

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7. Elevated serum HER‐2 predicts poor prognosis in breast cancer and is correlated to ADAM10 expression [O] . Hui Zheng, Ailing Zhong, Suhong Xie, 2019

机译：血清HER-2升高可预示乳腺癌的预后不良并且与ADAM10表达相关
8. Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity [O] . Gooden, M. J. M., Wiersma, V. R., Boerma, A., 2014

机译：血清CXCL16升高是卵巢癌存活率低的独立预测因子，可能反映了转移前ADAM蛋白酶的活性

Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity

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