High plasma fibrinogen level represents an independent negative prognostic factor regarding cancer-specific metastasis-free as well as overall survival in a European cohort of non-metastatic renal cell carcinoma patients

摘要

Background: In recent years, plasma fibrinogen has been ascribed an important role in the pathophysiology of tumour cell invasion and metastases. A relatively small-scale study has indicated that plasma fibrinogen levels may serve as a prognostic factor for predicting clinical outcomes in non-metastatic renal cell carcinoma (RCC) patients.