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A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer

机译：贝伐单抗联合FOLFIRI一线治疗转移性结直肠癌的安全性和有效性的回顾性观察研究

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摘要

Background: Combination of bevacizumab and FOLFIRI has currently become one of the standard therapeutic regimens. However, published information is still limited. The objective of the present retrospective observational study is to analyse the response and toxicity of first-line treatment with FOLFIRI+bevacizumab in patients with metastatic colorectal cancer (mCRC).

机译：背景：贝伐单抗和FOLFIRI的组合目前已成为标准治疗方案之一。但是，发布的信息仍然有限。本回顾性观察性研究的目的是分析FOLFIRI +贝伐单抗一线治疗转移性结直肠癌（mCRC）患者的反应和毒性。

著录项

期刊名称 British Journal of Cancer
作者
R López; M Salgado; M Reboredo; C Grande; J C Méndez; M Jorge; C Romero; G Quintero; J de la Cámara; S Candamio;
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作者单位

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年(卷),期 2010(103),10
年度 2010
页码 1536–1541
总页数 6
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
colorectal cancer bevacizumab FOLFIRI first-line treatment;

机译：大肠癌;贝伐单抗;FOLFIRI;一线治疗;

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专利

1. A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer [J] . R López, M Salgado, M Reboredo, British Journal of Cancer . 2010,第10期

机译：贝伐单抗联合FOLFIRI一线治疗转移性结直肠癌的安全性和有效性的回顾性观察研究
2. Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study. [J] . Van Cutsem E, Rivera F, Berry Annals of oncology: official journal of the European Society for Medical Oncology . 2009,第11期

机译：贝伐单抗联合FOLFOX，XELOX，FOLFIRI和氟嘧啶在转移性结直肠癌中的安全性和有效性：BEAT研究。
3. Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study [J] . E. Van Cutsem1* F. Rivera2 S. Berry3 A. Kretzschmar4 M. Michael5 M. DiBartolomeo6 M.-A. Mazier7 J.-L. Canon8 V. Georgoulias9 M. Peeters10 J. Bridgewater11 D. Cunningham12 and on behalf of the First BEAT investigators Annals of Oncology . 2009,第11期

机译：贝伐单抗联合FOLFOX，XELOX，FOLFIRI和氟嘧啶在转移性结直肠癌中的安全性和有效性：BEAT研究
4. Correlation between development of hypertension and efficacy in metastatic colorectal cancer patients treated with bevacizumab [C] . Horinouchi Y., Sakurada T., Nakamura T., European Association for Clinical Pharmacology and Therapeutics . 2011

机译：北伐单抗治疗转移性结直肠癌患者高血压与疗效的相关性
5. A phase Ib study of safety and pharmacokinetics of trastuzumab emtansine and pertuzumab in Japanese patients with HER2-positive metastatic breast cancer [D] . NOGUCHI, Emi 2019

机译：Ib期研究曲妥珠单抗氨丹宁和帕妥珠单抗在日本HER2阳性转移性乳腺癌患者中的安全性和药代动力学
6. Survival benefit and safety of the combinations of FOLFOXIRI ± bevacizumab versus the combinations of FOLFIRI ± bevacizumab as first-line treatment for unresectable metastatic colorectal cancer: a meta-analysis [O] . Wei Xu, Meng Kuang, Yang Gong, 2016

机译：FOLFOXIRI±贝伐单抗组合与FOLFIRI±贝伐单抗组合作为不可切除的转移性结直肠癌一线治疗的生存获益和安全性：一项荟萃分析
7. A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer [O] . López, R, Salgado, M, Reboredo, M, 2010

机译：贝伐单抗联合FOLFIRI一线治疗转移性结直肠癌的安全性和有效性的回顾性观察研究

A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer

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