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Clinical management of borderline tumours of the ovary: results of a multicentre survey of 323 clinics in Germany

机译:卵巢交界性肿瘤的临床管理:德国323家诊所的多中心调查结果

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摘要

The aim of this survey was to analyse the standard of care in diagnostic, surgery, chemotherapy and aftercare management for patients with borderline tumours of the ovary (BOTs) in Germany. A structured questionnaire comprising different dimensions was sent to all 1114 gynaecological departments. The questionnaire could be returned anonymously. The overall response rate was 29.0% (323 departments). Most departments were on secondary care (71.8%), tertiary care (23.2%) or university hospital (5.0%) level. Most clinicians performed not more than five BOT operations (89.2%) per year. Most departments (93.2%) used in addition to classical bimanual examination and vaginal ultrasound, tumour marker CA-125 detection, CT scan, MRI or PET-CT techniques. Departments in university and tertiary care hospitals performed more often a fresh frozen section (87 vs 64%). In young women, clinicians performed much seldom unilateral salpingo-oophorectomy (92%) and only in 53% biopsies of the contralateral ovary. Generally, biopsies of the contralateral ovary were performed in 4–53% of the patients. Chemotherapy was mostly favoured in ‘high-risk' patients with tumour residual, microinvasion or invasive implants. Thus, a high grade of insecurity in diagnostic and therapy of BOT exists in some gynaecological departments and underlines the need for more educational and study activities.
机译:这项调查的目的是分析德国患有卵巢交界性肿瘤(BOT)的患者在诊断,手术,化学疗法和术后护理方面的护理标准。一份包含不同维度的结构化问卷已发送给所有1114个妇科部门。问卷可以匿名返回。总体答复率为29.0%(323个部门)。大多数部门处于二级保健(71.8%),三级保健(23.2%)或大学医院(5.0%)的水平。大多数临床医生每年进行不超过5次BOT手术(占89.2%)。除经典的双手检查和阴道超声检查,肿瘤标志物CA-125检测,CT扫描,MRI或PET-CT技术外,大多数部门(93.2%)也使用了该技术。大学和三级医院的科室更常进行新鲜的冷冻切片(87比64%)。在年轻女性中,临床医生很少进行单侧输卵管卵巢切除术(92%),而对侧卵巢活检仅占53%。通常,对侧卵巢的活检在4–53%的患者中进行。对于有肿瘤残留,微浸润或浸润性植入物的“高风险”患者,化学疗法最受青睐。因此,一些妇科部门在诊断和治疗BOT方面存在高度的不安全感,并强调了开展更多教育和研究活动的必要性。

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