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美国卫生研究院文献>The Journal of Physiology
>Reduced ventricular flow propagation velocity in elite athletes is augmented with the resumption of exercise training
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Reduced ventricular flow propagation velocity in elite athletes is augmented with the resumption of exercise training
Chronic exercise induces physiological enlargement of the left ventricle (‘athlete's heart’), but the effects of current and long-term exercise training on diastolic function have not been investigated. Echocardiography and Doppler imaging were used to assess left ventricular (LV) dimensions and indices of diastolic filling in 22 elite athletes at the end of their ‘off-season’ (baseline) and, subsequently, following 3 and 6 months of training. Twelve matched controls were also studied at baseline, 3 and 6 months. Compared to controls at baseline, athletes exhibited significantly higher LV mass (235.7 ± 7.1 g versus 178.1 ± 14.5 g, P < 0.01) and reduced flow propagation velocity (VP: 50.21 ± 1.7 versus 72.2 ± 3.6 cm s−1, P < 0.01), a measure of diastolic function. Three months of training further increased LV mass in athletes (253.2 ± 7.1 g; P < 0.01 versus baseline), and significantly increased their VP (66.7 ± 2.5 cm s−1; P < 0.05 versus baseline). These trends for increased mass and diastolic filling persisted following 6 months of training (LV mass 249.0 ± 8.7 g P < 0.05 versus baseline; VP 75.7 ± 3.0 cm s−1; P < 0.01 versus baseline, and P = 0.01 versus 3 months). This study suggests that following a period of relative inactivity the rate of ventricular relaxation during early diastole may be slowed in athletes who exhibit ventricular hypertrophy, whilst resumption of training increases the speed of ventricular relaxation in the presence of further hypertrophy of the left ventricle.
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机译:慢性运动会诱发左心室(“运动员的心脏”)生理增大,但是目前和长期的运动训练对舒张功能的影响尚未得到研究。在22名“淡季”结束(基线)结束时以及随后的3个月和6个月的训练结束后,使用超声心动图和多普勒成像技术评估了22名优秀运动员的左心室(LV)尺寸和舒张期充盈指数。在基线,3个月和6个月时也研究了十二个匹配的对照。与基线时的对照组相比,运动员的左心室质量明显更高(235.7±7.1 g对178.1±14.5 g,P <0.01),血流传播速度降低(VP:50.21±1.7对72.2±3.6 cm s < / sup>,P <0.01),衡量舒张功能。三个月的训练进一步增加了运动员的左心室重量(253.2±7.1 g;与基线相比,P <0.01),并显着提高了他们的VP(66.7±2.5 cm s -1 sup>;与基线相比,P <0.05) 。训练6个月后,这些增加的重量和舒张压增加的趋势持续存在(左室重量249.0±8.7 g P <0.05,相对于基线; VP 75.7±3.0 cm s -1 sup>; P <0.01,相对于基线,以及P = 0.01 相对 em> 3个月)。这项研究表明,经过一段时间的相对运动后,表现出心室肥大的运动员舒张早期早期的心室放松速度可能会减慢,而在左心室进一步肥大的情况下,恢复训练可以提高心室放松的速度。
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