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Preventive Pap-smears: balancing costs risks and benefits.

机译:预防子宫颈抹片检查:平衡成本风险和收益。

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摘要

The pattern of spontaneous screening for cervical cancer by general practitioners and gynaecologists in The Netherlands is compared with an efficient screening policy resulting from a cost-effective study. Spontaneous screening tends to start and stop too early in a woman's life, and leaves too many women overscreened or unprotected. The combination in young age of a low incidence of invasive cancer and a high incidence of regressive lesions explains relative ineffectiveness and harmfulness of present screening practice. When screening would take place between ages 30 and at least 60, with intervals of about 5 years, as many lives could be saved for half the costs and with only 60% of the unnecessary referrals and treatments. Much attention should be paid to the coverage of the target population. Therapeutic follow-up policies for dysplastic lesions should be restrained.
机译:荷兰的全科医生和妇科医生对宫颈癌的自发筛查模式与一项具有成本效益的研究产生的有效筛查策略进行了比较。自发性筛查往往在女人的生命中过早地开始和停止,并且使过多的妇女受到过度筛查或未受到保护。年轻人中浸润性癌症发病率低而退化性病变发病率高的组合解释了目前筛查实践的相对无效性和有害性。当筛查发生在30岁至60岁之间,间隔大约5年时,因为只有60%的不必要的转诊和治疗可以挽救许多生命,而费用却只有一半。应该非常注意目标人群的覆盖范围。对于异常增生性病变的治疗随访政策应予以限制。

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