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The Amsler chart: absence of evidence is not evidence of absence

机译:阿姆斯勒图:缺乏证据不是缺乏证据

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摘要

Early detection of the onset or progression of macular disease is likely to become increasingly important as new treatment modalities are introduced. Current best practice involves issuing patients with an Amsler chart for daily or weekly observation with the instruction to attend for immediate assessment should any new distortion be perceived. However the sensitivity of Amsler charts in detecting macular disease can be less than 50%, implying that presentation may be delayed in over half of patients with advancing disease relying on the Amsler chart to detect progression. A likely explanation for this is the phenomenon of perceptual completion whereby regular objects are “filled‐in” across the scotoma. Although alternative tests have been developed and shown to have greater sensitivity, at present no straightforward, cheap, home‐based test of macular disease progression is available. The development of such a self‐diagnostic tool should be a research priority.
机译:随着引入新的治疗方式,黄斑疾病的发作或进展的早期检测可能变得越来越重要。当前的最佳实践包括发布带有Amsler图表的患者以进行每日或每周观察,并指导患者在发现任何新的变形时立即进行评估。但是,Amsler图表检测黄斑疾病的敏感性可能低于50%,这意味着依靠Amsler图表检测病情进展的半数以上疾病进展患者可能会出现延迟。对此的一种可能解释是感知完成的现象,即规则物体被“填满”到整个暗光斑中。尽管已经开发出替代测试并显示出更高的灵敏度,但目前尚无直接,便宜,基于家庭的黄斑疾病进展测试。开发这种自我诊断工具应该是研究的重点。

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