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Results of small incision extracapsular cataract surgery using the anterior chamber maintainer without viscoelastic

机译:小切口切口白内障白内障手术使用前房保持器而无粘弹性的结果

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摘要

AIMS—To assess the efficacy of extracapsular cataract surgery using the anterior chamber maintainer (ACM) without the use of viscoelastic. To compare the effects of this surgical technique on non-diabetic and diabetic patients.
METHODS—A prospective single armed clinical trial of 46 eyes in 46 patients undergoing cataract surgery using the ACM without viscoelastic. Patients were assessed preoperatively and at 3 weeks, 3 months, and 12 months postoperatively. The main outcome variables included visual acuity, surgically induced astigmatic change (SIAC), changes in endothelial cell density (ECD), and morphology affecting the central and superior regions of the cornea.
RESULTS—Postoperatively, 56% and 70% of patients had unaided visual acuities of 6/12 or better at 3 weeks and 3 months respectively. Even after excluding those patients with pre-existing maculopathy (including diabetic maculopathy), there remains a significant difference between the non-diabetic and diabetic groups in terms of the proportion of patients attaining an unaided visual acuity of 6/12 or better at both 3 weeks (p=0.003) and 3 months (p=0.001). Three months postoperatively, the SIAC based upon the keratometric and refractive data was 1.1 dioptres (D) and 1.3 D respectively. There was no statistically significant difference in the SIAC when the non-diabetic and diabetic groups were compared. The mean central and superior endothelial cell losses at 3 months postoperatively were 16% and 22% respectively and at 12 months postoperatively were 20% and 25% respectively. The diabetic group demonstrated greater endothelial cell losses and a more marked and protracted deviation of endothelial cell morphology from normality when compared with the non-diabetic group; however, the differences did not reach statistical significance.
CONCLUSIONS—The efficacy of small incision cataract surgery using the ACM in terms of visual outcome and induced astigmatism is comparable with the results obtained using other techniques that utilise a similar size of incision. However, in view of the magnitude and range of the endothelial cell losses associated with this technique the concurrent use of viscoelastic is suggested. There does not appear to be a statistically or clinically significant difference between non-diabetic and diabetic patients in terms of the magnitude of the endothelial cell losses or in the wound healing response in the 12 months after cataract surgery using the ACM.

Keywords: extracapsular cataract surgery; anterior chamber maintainer
机译:目的:评估使用前房保持器(ACM)而不使用粘弹性的白内障囊外手术的疗效。比较该手术技术对非糖尿病和糖尿病患者的效果。术前以及术后3周,3个月和12个月对患者进行评估。主要结局变量包括视力,手术诱发的散光变化(SIAC),内皮细胞密度(ECD)的变化以及影响角膜中央和上方区域的形态。
结果-术后,分别为56%和70%的患者在3周和3个月时的独立视力分别为6/12或更高。即使将那些既往患有黄斑病变(包括糖尿病性黄斑病变)的患者排除在外,非糖尿病组和糖尿病组之间仍然存在明显的差异,即在这两个方面获得独立视敏度达到6/12或更高的患者比例3周(p = 0.003)和3个月(p = 0.001)。术后三个月,基于角膜曲率和屈光数据的SIAC分别为1.1屈光度(D)和1.3屈光度。比较非糖尿病组和糖尿病组时,SIAC的差异无统计学意义。术后3个月的中央和上层内皮细胞​​平均损失分别为16%和22%,术后12个月的平均内皮细胞损失分别为20%和25%。与非糖尿病组相比,糖尿病组表现出更大的内皮细胞损失,并且内皮细胞形态与正常状态的差异更明显和更持久。但是,差异并未达到统计学意义。
结论—使用ACM进行小切口白内障手术在视觉结果和诱发散光方面的疗效与使用其他类似切口尺寸的技术所获得的结果相当。然而,考虑到与该技术有关的内皮细胞损失的大小和范围,建议同时使用粘弹性。在使用ACM的白内障手术后的12个月内,非糖尿病患者和糖尿病患者在内皮细胞损失的幅度或伤口愈合反应方面似乎没有统计学或临床上的显着差异。

关键词:白内障囊外手术;手术治疗前房保持器

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