The pharmacokinetics of peginterferon lambda-1a following single dose administration to subjects with impaired renal function

机译：单剂量施用聚乙二醇干扰素lambda-1a对肾功能受损的受试者的药代动力学

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摘要

AimsThis open label study was conducted to assess the effect of renal impairment (RI) on the pharmacokinetics (PK) of peginterferon lambda-1a (Lambda).

机译：目的这项开放标签研究旨在评估肾功能不全（RI）对聚乙二醇化干扰素lambda-1a（Lambda）药代动力学（PK）的影响。

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期刊名称 British Journal of Clinical Pharmacology
作者
Matthew W Hruska; Robert Adamczyk; Elizabeth Colston; Michael Hesney; Michele Stonier; Heather Myler; Richard Bertz;
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作者单位

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年(卷),期 2015(80),3
年度 2015
页码 515–524
总页数 10
原文格式 PDF
正文语种
中图分类药学;
关键词
pharmacokinetics peginterferon lambda-1a renal impairment;

机译：药代动力学;聚乙二醇干扰素lambda-1a;肾功能不全;

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专利

1. The pharmacokinetics of peginterferon lambda-1a following single dose administration to subjects with impaired renal function [J] . Hruska Matthew W., Adamczyk Robert, Colston Elizabeth, British Journal of Clinical Pharmacology . 2015,第3期

机译：单剂量施用聚乙二醇干扰素lambda-1a对肾功能受损的受试者的药代动力学
2. The pharmacokinetics of peginterferon lambda‐1a following single dose administration to subjects with impaired renal function [J] . Hruska Matthew W., Adamczyk Robert, Colston Elizabeth, British journal of clinical pharmacology . 2015,第3期

机译：单次服用聚乙二醇干扰素lambda-1a对肾功能受损的受试者的药代动力学
3. Pharmacokinetics of tamsulosin in subjects with normal and varying degrees of impaired renal function: an open-label single-dose and multiple-dose study. [J] . Wolzt M, Fabrizii V, Dorner GT, European journal of clinical pharmacology . 1998,第4期

机译：坦索罗辛在肾功能正常和程度不同的受试者中的药代动力学：一项开放标签的单剂量和多剂量研究。
4. Optimal dose administration of renally excreted drugs [C] . Giuseppe Pesenti, Adriana Savoca, Davide Manca European Symposium on Computer Aided Chemical engineering . 2019

机译：肾外肿药的最佳剂量给药
5. Design evaluation for pharmacokinetic studies in patients with renal impairment [D] . Liu, Jin 2007

机译：肾功能不全患者药代动力学研究的设计评估
6. 705. Pharmacokinetics (PK) and Safety of Lefamulin (LEF) After Single Intravenous Dose Administration in Subjects With Impaired Renal Function and in Those Requiring Hemodialysis [O] . Wolfgang Wicha, Thomas C Marbury, James A Dowell, -1

机译：705.肾功能不全的受试者和需要血液透析的受试者单次静脉内给药后利福莫林（LEF）的药代动力学（PK）和安全性
7. 705. Pharmacokinetics (PK) and Safety of Lefamulin (LEF) After Single Intravenous Dose Administration in Subjects With Impaired Renal Function and in Those Requiring Hemodialysis [O] . Wolfgang Wicha, Thomas C Marbury, James A Dowell, 2019

机译：705.药代动力学（PK）和Lefamulin（LEF）在肾功能受试者中的单一静脉剂剂量给药后的静脉内剂量给药和需要血液透析的那些
8. Guidance for Industry. Pharmacokinetics in Patients with Impaired Renal Function211 Study Design, Data Analysis, and Impact on Dosing and Labeling [R] . 1998

机译：工业指南。肾功能受损患者的药代动力学211研究设计，数据分析以及对剂量和标记的影响

The pharmacokinetics of peginterferon lambda-1a following single dose administration to subjects with impaired renal function

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