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Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters

机译：使用免疫组织病理学和血红蛋白参数确定预测乳腺癌对新辅助化疗反应的早期治疗窗口

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BackgroundBreast cancer pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) varies with tumor subtype. The purpose of this study was to identify an early treatment window for predicting pCR based on tumor subtype, pretreatment total hemoglobin (tHb) level, and early changes in tHb following NAC.

机译：背景对新辅助化疗（NAC）的乳腺癌病理完全缓解（pCR）因肿瘤亚型而异。这项研究的目的是根据肿瘤亚型，治疗前总血红蛋白（tHb）水平和NAC后tHb的早期变化确定预测pCR的早期治疗窗口。

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期刊名称 Breast Cancer Research : BCR
作者
Quing Zhu; Susan Tannenbaum; Scott H. Kurtzman; Patricia DeFusco; Andrew Ricci Jr; Hamed Vavadi; Feifei Zhou; Chen Xu; Alex Merkulov; Poornima Hegde; Mark Kane; Liqun Wang; Kert Sabbath;
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年(卷),期 2018(20),-1
年度 2018
页码 56
总页数 17
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Predicting neoadjuvant chemotherapy Personalized medicine Near infrared imaging Ultrasound-guided optical imaging;

机译：预测新辅助化疗;个性化药物;近红外成像;超声引导光学成像;

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专利

1. Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer [J] . H. Raza Ali, Aliakbar Dariush, Elena Provenzano, Breast Cancer Research . 2016,第1期

机译：预处理活检的计算病理学将淋巴细胞密度鉴定为对乳腺癌新辅助化疗的反应预测的淋巴细胞密度
2. Optical imaging of breast cancer oxyhemoglobin flare correlates with neoadjuvant chemotherapy response one day after starting treatment [J] . Darren Roblyer, Shigeto Ueda, Albert Cerussi, Proceedings of the National Academy of Sciences of the United States of America . 2011,第38期

机译：乳腺癌氧合血红蛋白耀斑的光学成像与开始治疗后一天的新辅助化疗反应相关
3. Comparison of Model-Free and Model-Based Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Parameters for Predicting Breast Cancers' Response to Neoadjuvant Chemotherapy [J] . Journal of computer assisted tomography . 2020,第2期

机译：基于模型和模型的动态对比增强磁共振成像药代动力学参数的比较预测乳腺癌对Neoadjuvant化疗的反应
4. TOTAL HEMOGLOBIN REDUCTION IN THE TUMOR VOLUME CORRELATES WITH RESPONSE TO BREAST CANCER NEOADJUVANT CHEMOTHERAPY WITHIN TWO WEEKS OF TREATMENT [C] . Mirella Altoe, Alessandro Marone, Hyun K. Kim, Conference on advances in optics for biotechnology, medicine and surgery . 2019

机译：在两个星期内，肿瘤体积中的总血红蛋白减少与对乳腺癌新辅助化疗的反应相关
5. Using Preoperative Mri-guided Biopsies to Predict Pathologic Complete Response after Neoadjuvant Chemotherapy in Breast Cancer [D] . Kim, Jiyoon. 2019

机译：在乳腺癌新辅助化疗后使用术前Mri引导的活检来预测病理完全缓解
6. Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer [O] . H. Raza Ali, Aliakbar Dariush, Elena Provenzano, 2016

机译：预处理活检的计算病理学将淋巴细胞密度确定为乳腺癌新辅助化疗反应的预测因子
7. Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer [O] . H. Raza Ali, Aliakbar Dariush, Elena Provenzano, 2016

机译：预处理活检的计算病理学将淋巴细胞密度确定为乳腺癌新辅助化疗反应的预测因子

Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters

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