Post-burn breast reconstruction using an artificial dermis—a long-term follow-up

摘要

BackgroundFull thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options.Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis.