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Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of Bladder Cancer

机译：MMP-9和IL-8表达增加与膀胱癌预后不良有关

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摘要

>BackgroundExtracellular matrix homeostasis is strictly maintained by a coordinated balance between the expression of metalloproteinases (MMPs) and their inhibitors. The purpose of this study was to investigate whether the expression of MMP-9, MMP-2 and its specific inhibitors, are expressed in a reproducible, specific pattern and if the profiles are related to prognosis in Bladder Cancer (BC).

机译：>背景细胞内基质稳态是通过金属蛋白酶（MMPs）及其抑制剂之间的协调平衡来严格维持的。这项研究的目的是调查MMP-9，MMP-2及其特异性抑制剂的表达是否以可再现的特异性模式表达，以及这些谱是否与膀胱癌（BC）的预后有关。

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期刊名称 BMC Urology
作者
Sabrina Thalita Reis; Katia Ramos M Leite; Luís Felipe Piovesan; José Pontes-Junior; Nayara Izabel Viana; Daniel Kanda Abe; Alexandre Crippa; Caio Martins Moura; Sanarelly Pires Adonias; Miguel Srougi; Marcos Francisco Dall’Oglio;
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作者单位

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年(卷),期 2012(12),-1
年度 2012
页码 18
总页数 5
原文格式 PDF
正文语种
中图分类泌尿科学（泌尿生殖系疾病）;小儿泌尿科学;肾疾病;
关键词
Bladder cancer Matrix metalloproteinase Prognosis Diagnosis Gene expression;

机译：膀胱癌;基质金属蛋白酶;预后;诊断;基因表达;

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专利

1. Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of Bladder Cancer [J] . Sabrina T Reis, Katia Ramos M Leite, Luís F Piovesan, BMC Urology . 2012,第1期

机译：MMP-9和IL-8表达增加与膀胱癌预后不良有关
2. Increased expression of GGN promotes tumorigenesis in bladder cancer and is correlated with poor prognosis [J] . Wang Wentao, Li Changfu, Chen Yongsheng, Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2018,第期

机译：GGN的表达增加促进膀胱癌中的肿瘤内酯，与预后差相关
3. Endogenous BTG2 expression stimulates migration of bladder cancer cells and correlates with poor clinical prognosis for bladder cancer patients [J] . N Wagener, J Bulkescher, S Macher-Goeppinger, British Journal of Cancer . 2013,第4期

机译：内源性BTG2表达刺激膀胱癌细胞迁移并与膀胱癌患者的不良临床预后相关
4. Ido serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells [C] . Aikou Okamoto, Takashi Nikaido, Kazunori Ochia International Study Group for Tryptophan Research . 2007

机译：IDO用作浆液性卵巢癌细胞基因表达谱中预后不良的标志物
5. Cadherin-11mediation of tumor progression and invasion in poor prognosis cancers: A viable therapeutic target. [D] . Guidry Auvil, Jaime Marie. 2009

机译：在不良预后的癌症中，Cadherin-11介导的肿瘤进展和侵袭：可行的治疗靶点。
6. Endogenous BTG2 expression stimulates migration of bladder cancer cells and correlates with poor clinical prognosis for bladder cancer patients [O] . N Wagener, J Bulkescher, S Macher-Goeppinger, 2013

机译：内源性BTG2表达刺激膀胱癌细胞迁移并与膀胱癌患者的不良临床预后相关
7. Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of Bladder Cancer [O] . Reis, Sabrina Thalita, Leite, Katia Ramos M., Piovesan, Luis Felipe, 2013

机译：MMP-9和IL-8表达增加与膀胱癌预后不良有关

Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of Bladder Cancer

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