Impact of Once- Versus Twice-Daily Tacrolimus Dosing on MedicationAdherence in Stable Renal Transplant Recipients: A Canadian Single-CenterRandomized Controlled Trial

摘要

Background:Prevalence of immunosuppressant nonadherence in renal transplant recipients is high despite negative clinical outcomes associated with nonadherence. Simplification of dosing has been demonstrated to improve adherence in renal transplant recipients as measured through electronic monitoring and self-report.