Accurate diagnosis and effective therapeutics of uterine pathologies in cattle represent some of the daily preoccupations for the veterinarians involved in herd health medicine. A rational approach requires a competence based on fundamental and clinical knowledge.The physiological aspects of the uterine involution in cattle are reviewed with emphasis about the in utero bacteriological dynamic and the endocrinological evolution during this period. The pathogenesis of uterine pathologies is discussed following new research results and new knowledge on the mechanisms of uterine defense. The value and limitations of the clinical diagnosis is briefly reviewed. The therapeutics of uterine pathologies is debated in relation with the pathophysiology of the uterine involution and with the rational of the traditional and new concepts of the treatment of the postpartum uterine pathologies.
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