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Nonthrombotic Pulmonary Embolism: A Potential Complication of Polyacrylamide Hydrogel Cosmetic Injection

机译:非血栓性肺栓塞:聚丙烯酰胺水凝胶化妆品注射液的潜在并发症。

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摘要

Context. Polyacrylamide hydrogel (PAAG) has gained importance as a synthetic soft tissue filling agent. It has been commonly employed by physicians in Europe for facial contouring and soft tissue augmentation. Previously, PAAG is considered nontoxic and well tolerated with a few mild procedural complications. Case Presentation. A 26-year-old female was hospitalized for dry cough, worsening dyspnea, and chest discomfort after 3 hours of multiple PAAG injections in buttocks. The patient's condition deteriorated and rapidly advanced to acute respiratory failure. Therein, the diagnosis of nonthrombotic pulmonary embolism (NTPE) was established on standard set of investigations. She was intubated; corticosteroid and empiric antibiotic therapy was initiated resulting in improvement of her condition. Subsequently, extubation was done, and she was discharged from the hospital after an uneventful recovery. On 1-month follow-up, the patient had no previous symptoms. Conclusion. This report implicates clinicians to maintain a high index of suspicion for NTPE in patients presenting with respiratory symptoms following PAAG usage.
机译:上下文。聚丙烯酰胺水凝胶(PAAG)作为合成的软组织填充剂已变得越来越重要。它已被欧洲的医师普遍用于面部轮廓和软组织增强。以前,PAAG被认为是无毒且耐受性良好,并伴有一些轻度的手术并发症。案例介绍。在臀部多次注射PAAG 3小时后,一名26岁的女性因干咳,呼吸困难加重和胸部不适而住院。患者的病情恶化并迅速发展为急性呼吸衰竭。其中,非血栓性肺栓塞(NTPE)的诊断是根据一组标准的研究确定的。她被插了管。开始使用皮质类固醇和经验性抗生素治疗,从而改善了她的病情。随后,进行了拔管,并在恢复平稳后从医院出院。在1个月的随访中,患者没有先前的症状。结论。该报告暗示临床医生在使用PAAG后出现呼吸道症状的患者中高度怀疑NTPE。

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