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Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies

机译:具有继发于母体抗Ro抗体的完全性心脏传导阻滞的婴儿的阴道分娩

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摘要

Congenital heart block (CHB) is a rare disorder that may be associated with a high morbidity and even mortality, with a risk of death both in utero and during infancy. Women with serum titres of anti-Ro and/or anti-La antibodies carry a risk of CHB of 1–5% in their offspring, with a recurrence risk of approximately 20%. We present a case of a 36-year-old female with a pregnancy complicated by congenital heart block. Autoimmune profiling at booking showed she was positive for lupus anticoagulant and anti-Ro antibodies. A fetal echocardiogram at 21 + 3 showed complete heart block. She was monitored throughout the remainder of her pregnancy with serial growth scans, cardiovascular profiling, and BPP scoring. She had a normal vaginal delivery at term to a female infant.
机译:先天性心脏传导阻滞(CHB)是一种罕见的疾病,可能与高发病率甚至死亡相关,在子宫内和婴儿期都有死亡的危险。血清中具有抗Ro和/或抗La抗体滴度的女性在其子代中发生CHB的风险为1–5%,复发风险约为20%。我们介绍了一例36岁女性,其妊娠并发先天性心脏传导阻滞。预订时进行自身免疫分析,显示她的狼疮抗凝和抗Ro抗体阳性。 21 + 3的胎儿超声心动图显示完全的心脏传导阻滞。通过连续生长扫描,心血管分析和BPP评分对她在整个妊娠剩余期间进行监测。她足月对一名女婴的阴道分娩正常。

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