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Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention

机译：口服重组蛋氨酸酶（o-rMETase）靶向蛋氨酸可阻止BRAF-V600E突变型黑色素瘤的患者原位异种移植（PDOX）模型：对慢性临床癌症治疗和预防的意义

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期刊名称 Cell Cycle
作者
Kei Kawaguchi; Qinghong Han; Shukuan Li; Yuying Tan; Kentaro Igarashi; Tasuku Kiyuna; Kentaro Miyake; Masuyo Miyake; Bartosz Chmielowski; Scott D. Nelson; Tara A. Russell; Sarah M. Dry; Yunfeng Li; Arun S. Singh; Mark A. Eckardt; Michiaki Unno; Fritz C. Eilber; Robert M. Hoffman;
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年(卷),期 2018(17),3
年度 2018
页码 356–361
总页数 6
原文格式 PDF
正文语种
中图分类细胞生物学;
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1. Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention [J] . Kawaguchi Kei, Han Qinghong, Li Shukuan, Cell cycle . 2018,第3期

机译：用口服重组蛋氨酸酶（O-REMETASE）靶向甲硫氨酸（O-RMETASE）捕获BRAF-V600E突变体黑素瘤的患者衍生的原位异种移植（PDOX）模型：对慢性临床癌症治疗和预防的影响
2. Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention [J] . Kawaguchi Kei, Han Qinghong, Li Shukuan, Cell cycle . 2018,第3期

机译：用口服重组甲硫氨酸酶（O-RMETase）靶向甲硫氨酸（O-REMETASE）捕获BRAF-V600E突变体黑素瘤的患者衍生的原位异种移植（PDOX）模型：对慢性临床癌症治疗和预防的影响
3. Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer [J] . Kawaguchi Kei, Miyake Kentaro, Han Qinghong, Cell cycle . 2018,第7期

机译：用重组甲硫氨酸酶（RMETase）靶向改变的癌甲硫氨酸代谢克服了部分吉西众氏菌，并回归胰腺癌的患者衍生的原位异种移植物（PDOX）裸鼠癌症
4. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [C] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Molecular-Guided Surgery: Molecules, Devices, and Applications IV . 2018

机译：荧光人源化抗CEA抗体在源自患者的原位异种移植（PDOX）小鼠模型中特异性标记转移性胰腺癌
5. Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer [O] . Kei Kawaguchi, Kentaro Miyake, Qinghong Han, 2018

机译：用重组蛋氨酸酶（rMETase）靶向改变的蛋氨酸代谢可以克服吉西他滨的部分耐药性并使胰腺癌的患者原位异种移植（PDOX）裸鼠模型退化
6. Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer [O] . Kei Kawaguchi, Kentaro Miyake, Qinghong Han, 2018

机译：用重组甲硫氨酸酶（RMETase）靶向改变的癌甲硫氨酸代谢克服了部分吉西众氏菌，并回归胰腺癌的患者衍生的原位异种移植物（PDOX）裸鼠癌症

Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention

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