Effect of (R)-(+) Pulegone on Ovarian Tissue; Correlationwith Expression of Aromatase Cyp19 and OvarianSelected Genes in Mice

摘要

Objective Pulegone (PGN) is a monoterpene ketone, whose metabolites exert several cytotoxic effects in various tissues. The present study was conducted in order to evaluate the (R)-(+) PGN-induced alterations in ovarian aromatization, proto-oncogenes and estrogen receptorα (ERα) and ERβ receptors expressions.