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Use of cardiac troponin t rapid assay in the diagnosis of a myocardial injury secondary to electrical cardioversion

机译:心肌肌钙蛋白快速测定在电复律继发性心肌损伤的诊断中的应用

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摘要

Background and hypothesis: This study was carried out to determine whether cardiac troponin T test in rapid assay gives positive results in patients previously submitted to cardioversion or electrical defibrillation. Methods: Forty patients with supraventricular tachyarrhythmias lasting no more than 2 days were treated with electrical cardioversion. The total creatine phosphokinase (CPK)‐MB isoenzyme and troponin T in rapid assay were measured at baseline and at 6, 12, and 24 h thereafter. Results: Total CPK baseline levels were normal in all cases; within 4 h, the serum CPK levels increased by 98%, at 6 h by 111.5%, at 12h by 168%, and at 24 h by 225% (p<0.01). The CPK‐MB isoenzyme showed no percentage increase of total CPK higher than 5%, measured at 6, 12, and 24h after the shock, independent of the number of attempts of cardioversion. The troponin T test was also negative in all cases at baseline and at 6, 12, and 24 h after cardioversion. Conclusion: We conclude that the absence of elevations in CPK‐MB levels and cardiac troponin T levels matched clinical and electrocardiographic results showing absence of myocardial damage after electrical cardioversion.
机译:背景和假设:进行这项研究是为了确定快速检测中的心肌肌钙蛋白T测试在先前接受心脏复律或电除颤的患者中是否获得阳性结果。方法:对40例持续时间不超过2天的室上性快速性心律失常患者进行电转律治疗。在基线时以及之后的6、12和24小时,对快速测定中的总肌酸磷酸激酶(CPK)-MB同工酶和肌钙蛋白T进行了测量。结果:所有病例的总CPK基线水平均正常;在4小时内,血清CPK水平增加了98%,在6小时时增加了111.5%,在12小时时增加了168%,在24小时时增加了225%(p <0.01)。 CPK-MB同工酶显示,在电击后第6、12和24小时测得的总CPK高于5%的百分比没有增加,与复律尝试次数无关。在所有情况下,在基线以及心脏复律后6、12和24小时,肌钙蛋白T检验均为阴性。结论:我们得出的结论是,CPK-MB水平和心肌肌钙蛋白T水平没有升高,与临床和心电图结果相符,表明电复律后没有心肌损害。

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