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AIT (allergen immunotherapy): a model for the precision medicine

机译:AIT(过敏原免疫疗法):精密药物的模型

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摘要

The interpretation of medical approaches, especially therapy, evolved rapidly in the last century. Starting from the simple description of symptoms, we moved to the pathophysiological descriptions, to the evidence-based medicine, until the so-called “precision medicine”. This latter can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level. In this sense, allergen immunotherapy represents an optimal model of “precision medicine”, since we know and describe symptoms, function, aetiological agents at molecular level, and we have the possibility to intervene on the natural history of the disease. If considered under the point of view of pharmaco-economy, that is prescribing the optimal treatment to the right patient, allergen immunotherapy represents an almost-ideal model of precision medicine.
机译:在上个世纪,对医学方法尤其是治疗方法的解释迅速发展。从简单的症状描述开始,我们转向了病理生理学描述,转向了循证医学,直到所谓的“精密医学”。后者可以定义为旨在定制医疗保健的结构模型,并针对每个患者量身定制高度详细的医疗决策/产品。从这个意义上讲,过敏原免疫疗法代表了“精确医学”的最佳模型,因为我们在分子水平上了解并描述了症状,功能,病因,并且我们有可能干预该疾病的自然病史。如果从药物经济学的角度考虑,即为正确的患者开出最佳治疗方案,则过敏原免疫疗法几乎代表了理想的精确医学模型。

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