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Efficacy of tenofovir-based rescue therapy for chronic hepatitis B patients with resistance to lamivudine and entecavir

机译：基于替诺福韦的抢救治疗对拉米夫定和恩替卡韦耐药的慢性乙型肝炎患者的疗效

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摘要

Background/AimsTenofovir disoproxil fumarate (TDF) monotherapy for 48 weeks provided a virological response comparable to that of TDF and entecavir (ETV) combination therapy in patients infected with ETV-resistant hepatitis B virus (HBV). Little long-term data in routine clinical practice are available regarding the optimal treatment of patients with ETV-resistant HBV.

机译：背景/目的替诺福韦富马酸替索罗非酯（TDF）单一疗法治疗感染ETV耐药性乙型肝炎病毒（HBV）的患者提供的病毒学应答与TDF和恩替卡韦（ETV）联合疗法相当。在常规临床实践中，很少有关于ETV耐药性HBV患者最佳治疗的长期数据。

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期刊名称 Clinical and Molecular Hepatology
作者
Hee-Jeong Jeon; Seok Won Jung; Neung Hwa Park; Yujin Yang; Jin-Hee Noh; Jae-Sung Ahn; Hyung Rae Kim; Jae Ho Lee; Jung Woo Shin;
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作者单位

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年(卷),期 2017(23),3
年度 2017
页码 230–238
总页数 9
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
Tenofovir Resistance Lamivudine Entecavir Chronic hepatitis B;

机译：替诺福韦;抗药性;拉米夫定;恩替卡韦;慢性乙型肝炎;

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专利

1. Tenofovir-based rescue therapy for chronic hepatitis B patients who had failed treatment with lamivudine, adefovir, and entecavir [J] . Kim Byung Gyu, Jung Seok Won, Kim Eun Hye, Journal of gastroenterology and hepatology . 2015,第10期

机译：基于替诺福韦的慢性乙型肝炎患者的拉米夫定，阿德福韦和恩替卡韦治疗失败的抢救疗法
2. Efficacy of Tenofovir-based Rescue Therapy in Lamivudine-resistant Chronic Hepatitis B Patients With Failure of Lamivudine and Adefovir Combination [J] . Park Jae Ho, Jung Seok Won, Park Neung Hwa, Clinical therapeutics . 2015,第7期

机译：替诺福韦的抢救疗法对拉米夫定耐药和阿德福韦酯联合耐药的慢性乙型肝炎患者的疗效
3. Efficacy of adefovir add-on lamivudine rescue therapy compared with switching to entecavir monotherapy in patients with lamivudine-resistant chronic hepatitis B. [J] . Ryu HJ, Lee JM, Ahn SH, Journal of Medical Virology . 2010,第11期

机译：阿德福韦联合拉米夫定抢救治疗与耐药性拉米夫定慢性乙型肝炎患者转用恩替卡韦单药治疗的疗效比较。
4. Mathematical modeling based on lamivudine switching to adefovir dipivoxil and to entecavir anti-hepatitis B infection treatment [C] . IEEE 5th International Bio-Inspired Computing: Theories and Applications . 2010

机译：基于拉米夫定转为阿德福韦酯和恩替卡韦抗乙型肝炎感染治疗的数学模型
5. Population pharmacokinetics and efficacy of ribavirin in patients with chronic hepatitis C genotype 1 infection. [D] . Jin, Runyan. 2010

机译：利巴韦林在慢性丙型肝炎基因型1感染患者中的群体药代动力学和功效。
6. Efficacy and resistance in de novo combination lamivudine and adefovir dipivoxil therapy versus entecavir monotherapy for the treatment-naive patients with chronic hepatitis B: a meta-analysis [O] . Fen Liu, Xiwei Wang, Fang Wei, 2014

机译：从头开始拉米夫定联合阿德福韦酯联合恩替卡韦单药治疗初治慢性乙型肝炎的疗效和耐药性：一项荟萃分析
7. Efficacy of tenofovir-based rescue therapy for chronic hepatitis B patients with resistance to lamivudine and entecavir [O] . Hee-Jeong Jeon, Seok Won Jung, Neung Hwa Park, 2017

机译：替诺福韦救治疗法对拉米夫定和恩替卡韦耐药的慢性乙型肝炎患者的疗效

Efficacy of tenofovir-based rescue therapy for chronic hepatitis B patients with resistance to lamivudine and entecavir

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