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Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia

机译:核心处的寒冷:神经结节病引起的中央体温过低的奥斯本波

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摘要

Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently been attributed to a voltage differential between epicardial and endocardial potassium (Ito) currents. While the exact conditions required to induce such waves have been debated, numerous clinical scenarios of environmental and iatrogenic hypothermia have been described. Below, we report a novel case of hypothermia—that of neurosarcoidosis-induced central hypothermia with resultant Osborn waves and other associated findings found on electrocardiogram (ECG).
机译:奥斯本波或J波最初由约翰·奥斯本(John Osborn)在1953年进行的低温犬实验中描述,对低温非常敏感且具有特异性。最初被认为是亚低温引起的“损伤电流”的继发因素,最近它们被归因于心外膜和心内膜钾(Ito)电流之间的电压差。尽管引发此类波所需的确切条件已受到争议,但已描述了环境和医源性体温过低的许多临床情况。以下,我们报告了一种低温症的新病例-神经结节病引起的中央体温过低,并伴有奥斯本波和在心电图(ECG)上发现的其他相关发现。

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