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HIV diagnoses and missed opportunities. Results of the British HIV Association (BHIVA) National Audit 2010

机译:HIV诊断和错过机会。英国艾滋病协会(BHIVA)国家审计结果2010

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摘要

The late diagnosis of HIV in patients across the UK is an increasing problem. Here, we report on a retrospective case-notes audit carried out to assess the impact of the 2008 UK HIV testing guidelines on clinical practice and identify missed opportunities for HIV testing. The audit was carried out in 2010 and focussed on patients with newly diagnosed HIV at centres providing adult HIV services across the UK. Data were collected on 1,112 patients, of whom 52.2% were found to have a late HIV diagnosis as defined as a CD4 T lymphocyte count of <350 cells/mm3. Most patients (62.6%) were diagnosed in traditional settings, with a significant increase in those diagnosed with HIV in non-traditional settings (33%) compared with the 2003 audit (18.5%) (p<0.001). The most frequent indicator conditions that patients had experienced were chronic diarrhoea or weight loss, sexually transmitted infection, blood dyscrasia or lymphadenopathy. A quarter of patients were identified as having had a missed opportunity for earlier diagnosis. Based on our results, we suggest that HIV testing needs to continue to expand across clinical settings to reduce the number of patients living with undiagnosed HIV infection.
机译:在英国,对艾滋病患者的晚期诊断是一个日益严重的问题。在这里,我们报告一项回顾性病例注释审核,以评估2008年英国HIV检测指南对临床实践的影响,并确定错过的HIV检测机会。审核于2010年进行,重点是在英国各地提供成人HIV服务的中心,对新诊断为HIV的患者进行检查。收集了1,112例患者的数据,其中发现52.2%的HIV晚期诊断为CD4 T淋巴细胞计数<350细胞/ mm 3 。大多数患者(62.6%)被诊断为传统环境,与2003年的审核(18.5%)相比,非传统背景下被诊断为HIV的患者(33%)显着增加(p <0.001)。患者经历的最常见的指示病是慢性腹泻或体重减轻,性传播感染,血液异常和淋巴结病。确认四分之一的患者错过了早期诊断的机会。根据我们的结果,我们建议艾滋病毒检测需要继续扩大到整个临床环境,以减少未确诊的艾滋病毒感染患者的数量。

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