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Topical ocular 0.1 cyclosporine A cationic emulsion in dry eye disease patients with severe keratitis: experience through the French early-access program

机译：干眼症重度角膜炎患者的局部眼用0.1％环孢素A阳离子乳剂：法国早期抢救计划的经验

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摘要

PurposeThe objective of this study was to report the evaluation of efficacy and safety of cyclosporine A cationic emulsion (CsA CE) 0.1% for the treatment of severe keratitis in adults with dry eye disease (DED) in a French early-access program.

机译：目的这项研究的目的是在法国的一项抢先计划中报告0.1％的环孢素A阳离子乳剂（CsA CE）对成人干眼症（DED）严重角膜炎的治疗效果和安全性评估。

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期刊名称 Clinical Ophthalmology (Auckland N.Z.)
作者
Pierre-Jean Pisella; Marc Labetoulle; Serge Doan; Beatrice Cochener-Lamard; Mourad Amrane; Dahlia Ismail; Catherine Creuzot-Garcher; Christophe Baudouin;
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作者单位

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年(卷),期 2018(12),-1
年度 2018
页码 289–299
总页数 11
原文格式 PDF
正文语种
中图分类眼科学;
关键词
dry eye keratoconjunctivitis sicca cyclosporine A Sjögren’s syndrome inflammation cationic emulsion severe keratitis Ikervis;

机译：干眼症;干燥性角结膜炎;环孢素A;干燥综合征;炎症;阳离子乳剂;严重的角膜炎;Ikervis;

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专利

1. Topical ocular 0.1% cyclosporine A cationic emulsion in dry eye disease patients with severe keratitis: experience through the French early-access program [J] . Pierre-Jean Pisella, Marc Labetoulle, Serge Doan, Clinical ophthalmology . 2018,第2期

机译：干眼症重度角膜炎患者的局部眼用0.1％环孢素A阳离子乳剂：法国早期抢救计划的经验
2. Topical ocular ciclosporin 1 mg/mL cationic emulsion in patients with dry eye with severe keratitis: Experience through the French early access program [J] . Doan Serge, Pisella Pierre-Jean, Cochener Beatrice, Investigative ophthalmology & visual science . 2016,第12期

机译：局部眼皮孢菌素1 mg / ml阳离子乳液，干眼症患者严重角膜炎：经验通过法国早期访问计划
3. Persistence of Efficacy of 0.1% Cyclosporin A Cationic Emulsion in Subjects with Severe Keratitis Due to Dry Eye Disease: A Nonrandomized, Open-label Extension of the SANSIKA Study [J] . Labetoulle Marc, Leonardi Andrea, Amrane Mourad, Clinical therapeutics . 2018,第11期

机译：持续0.1％环孢菌素阳离子乳液在具有干眼症的严重角膜炎的受试者中的阳离子乳液的效果：非扫描，开放标签延伸的梭景观研究
4. Assessment of the efficacy of topical cyclosporine for Dry Eye Disease induced by mustard gas using tear osmolarity measurement [C] . Jadidi K., Ebrahimi A., Rezaee M., International Symposium on Ocular Pharmacology and Therapeutics . 2013

机译：用泪液测量评估芥子气体诱导的芥子气体诱导的干眼症疗效的疗效
5. The effect of a topical ocular preparation on performance of simulated driving in cases of symptomatic dry eye. [D] . Mickles, Chandra V. 2012

机译：在有症状的干眼情况下，局部眼用制剂对模拟驾驶性能的影响。
6. Preclinical Efficacy Comparison of Cyclosporine Ophthalmic Solution 0.09 vs Cyclosporine Ophthalmic Emulsion 0.05 vs Ciclosporin Ophthalmic Emulsion 0.1 in a NOD Mouse Model of Dry Eye Disease [O] . Vinod Burade, Rishit Zalawadia, Alpesh Patel, 2020

机译：环孢菌素眼科溶液的临床前疗效比较0.09％Vs环孢菌素眼科乳液0.05％Vs Ciclosporin眼科乳液0.1％在Dry眼病的点小鼠模型中
7. Persistence of Efficacy of 0.1 Cyclosporin A Cationic Emulsion in Subjects with Severe Keratitis Due to Dry Eye Disease: A Nonrandomized, Open-label Extension of the SANSIKA Study [O] . Marc Labetoulle, Andrea Leonardi, Mourad Amrane, 2018

机译：持续0.1％环孢菌素阳离子乳液在具有干眼症的严重角膜炎的受试者中的阳离子乳液的效果：非扫描，开放标签延伸的梭景观研究

Topical ocular 0.1 cyclosporine A cationic emulsion in dry eye disease patients with severe keratitis: experience through the French early-access program

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