首页> 美国卫生研究院文献>ClinicoEconomics and Outcomes Research: CEOR >Body mass characteristics of hip osteoarthritis patients experiencing aseptic loosening periprosthetic fractures dislocation and infections after total hip replacement
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Body mass characteristics of hip osteoarthritis patients experiencing aseptic loosening periprosthetic fractures dislocation and infections after total hip replacement

机译:全髋关节置换术后出现无菌性松动假体周围骨折脱位和感染的髋骨关节炎患者的体重特征

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摘要

This work assessed the body mass characteristics of a cohort of community dwelling adults requiring surgery for complications related to primary hip arthroplasty, among other factors. The specific aim was to identify the extent to which high body mass prevailed in the cohort as a whole, to identify a role for subnormal body mass in the pathogenesis of post-operative complications following hip joint arthroplasty, and to identify whether different complication types could be differentiated on the basis of body mass profiles. The subjects were males and females drawn from a representative sample of 1,040 hip osteoarthritis patients between the ages of 30–89 years hospitalized for purposes of primary hip arthroplasty or complications related to prior replacement surgery. An analysis of their medical records showed: 1) Approximately 20% of the present cohort was constituted by patients with various complications related to prior arthroplasties, or to general deterioration of their condition; 2) The most common reasons for their re-hospitalization were aseptic prosthetic loosening followed by infection, prosthetic dislocations, prosthetic and periprosthetic fractures, and second surgeries on the opposite hip; 3) The presence of a high body mass index differentiated those presenting with aseptic prosthetic loosening, periprosthetic fractures, and those with infected hips (p < 0.007). Those with infection diagnoses were significantly heavier on average than those with no infection, regardless of diagnosis, and more cases with a dislocation history were underweight, rather than overweight (p < 0.05). It is concluded, a small but clinically relevant proportion of obese or underweight adults with hip osteoarthritis who undergo primary total hip replacement may experience complications at higher rates than cases with normal body weight, despite the generally successful outcomes experienced by the majority of hip arthroplasty patients.
机译:这项工作评估了一群社区居民的体重特征,这些成年人因与原发性髋关节置换术相关的并发症而需要手术治疗。具体目的是确定整个队列中高体重人群的患病率,确定不正常体重在髋关节置换术后并发症的发病机理中的作用,并确定不同的并发症类型是否可以根据体重状况进行区分。研究对象是男性和女性,这些患者来自代表性的1040例30-89岁的髋骨关节炎患者,这些患者因原发性髋关节置换术或与先前置换手术相关的并发症而住院。对他们的病历的分析表明:1)目前队列中约20%由患有与先前关节置换术或病情普遍恶化相关的各种并发症的患者组成; 2)再次住院的最常见原因是无菌假体松动,继发感染,假体脱位,假体和假体周围骨折以及对侧髋关节的第二次手术; 3)高体重指数的存在将无菌假体松动,假体周围骨折和髋部感染的假体区别开来(p <0.007)。不论诊断如何,被诊断为感染的患者平均比没有感染的患者重得多,并且有脱位病史的病例体重不足而不是超重(p <0.05)。结论是,尽管大多数髋关节置换术患者普遍取得了成功的结果,但一小部分但在临床上相关的肥胖或体重不足的成年人进行全髋关节置换手术的并发症可能比正常体重的病例发生率更高。 。

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