Pharmacokinetics of neutron-irradiated meglumine antimoniate inLeishmania amazonensis-infected BALB/c mice

机译：中子辐照葡甲胺锑酸盐在体内的药代动力学亚马逊利什曼原虫感染的BALB / c小鼠

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: Cutaneous leishmaniasis (CL) is a parasitic disease caused by the protozoan Leishmania spp. Pentavalent antimonial agents have been used as an effective therapy, despite their side effects and resistant cases. Their pharmacokinetics remain largely unexplored. This study aimed to investigate the pharmacokinetic profile of meglumine antimoniate in a murine model of cutaneous leishmaniasis using a radiotracer approach.

机译：背景：皮肤利什曼病（CL）是由原生动物利什曼原虫（Leishmania spp）引起的寄生虫病。五价锑剂尽管有副作用和耐药性，但仍被用作有效疗法。他们的药代动力学仍未开发。这项研究的目的是研究使用放射性示踪方法在皮肤利什曼病的鼠模型中葡甲胺锑酸盐的药代动力学特征。

著录项

期刊名称 The Journal of Venomous Animals and Toxins Including Tropical Diseases
作者
Samanta Etel Treiger Borborema; João Alberto Osso Junior; Heitor Franco de Andrade Junior; Nanci do Nascimento;
展开▼
作者单位

展开▼
年(卷),期 2019(25),-1
年度 2019
页码 e144618
总页数 9
原文格式 PDF
正文语种
中图分类毒物学（毒理学）;
关键词
cutaneous leishmaniasis meglumine antimoniate pharmacokinetics biodistribution antimony radioisotope;

机译：皮肤利什曼病;葡甲胺锑酸盐;药代动力学;生物分布;锑;放射性同位素;
入库时间 2022-08-17 11:46:50

相似文献

外文文献
中文文献
专利

1. Pharmacokinetics of neutron-irradiated meglumine antimoniate inLeishmania amazonensis-infected BALB/c mice [J] . Samanta Etel Treiger Borborema, Jo?o Alberto Osso Junior, Heitor Franco de Andrade Junior, Journal of venomous animals and toxins . 2019,第2016期

机译：中子辐照葡甲胺锑酸盐在亚马逊利什曼原虫感染的BALB / c小鼠中的药代动力学
2. The activity of encapsulated meglumine antimoniate in stearylamine-bearing liposomes against cutaneous leishmaniasis in BALB/c mice [J] . Experimental parasitology . 2019,第期

机译：在BALB / C小鼠中对硬脂胺脂质体抗皮肤Leishmaniaisis的封装Meglumine锑酸酯的活性
3. Effect of hydroalcoholic extract of Echinacea purpurea in combination with meglumine antimoniate on treatment of Leishmania major-induced cutaneous leishmaniasis in BALB/c mice [J] . Bahador Sarkari, Mobin Mohseni, Mahmoud Reza Moein, International Journal of Applied and Basic Medical Research . 2017,第1期

机译：紫锥菊的水醇提取物与葡甲胺锑酸盐合用对严重利什曼原虫诱导的BALB / c小鼠皮肤利什曼病的治疗
4. Pharmacokinetics of multiple-dose subcutaneous fiunixin meglumine in lactating dairy goats [C] . J.S. Smith, J.A. Angelos, J.D. Rowe, Annual Conference of the American^Association^of^Bovine^Practitioners., Conference . 2014

机译：哺乳乳制山羊多剂皮下杂皮山脉颌骨动力学的药代动力学
5. Sensitization to a Milk Allergen Induces Differential Behavioral and Neurological Responses in Allergic C57BL/6J and BALB/cJ Mice [D] . Smith, Nicholas. 2021

机译：对乳过敏原的敏化诱导过敏性C57BL / 6J和BALB / CJ小鼠中的差异行为和神经响应
6. Mixed Formulation of Conventional and Pegylated Meglumine Antimoniate-Containing Liposomes Reduces Inflammatory Process and Parasite Burden in Leishmania infantum-Infected BALB/c Mice [O] . Levi Eduardo Soares Reis, Rory Cristiane Fortes de Brito, Jamille Mirelle de Oliveira Cardoso, 2017

机译：常规和聚乙二醇化的含聚葡甲胺的含锑脂质体的混合制剂可降低婴儿利什曼原虫感染的BALB / c小鼠的炎症过程和寄生虫负担
7. Biodistribution of meglumine antimoniate in healthy and Leishmania (Leishmania) infantum chagasi-infected BALB/c mice [O] . Samanta Etel Treiger Borborema, João Alberto Osso Junior, Heitor Franco de Andrade Junior, 2013

机译：嗜酸葡甲胺在健康和利什曼原虫（利什曼原虫）Chagas感染的婴儿BaLB / c小鼠中的生物分布
8. Comparison of Meglumine Antimoniate and Pentamidine for Peruvian Cutaneous Leishmaniasis [R] . Andersen, E. M. , Cruz-Saldarriaga, M. , Llanos-Cuentas, A. , 2005

机译：葡甲胺锑酸盐与喷他脒对秘鲁皮肤利什曼病的比较

Pharmacokinetics of neutron-irradiated meglumine antimoniate inLeishmania amazonensis-infected BALB/c mice

摘要

著录项

相似文献

相关主题

期刊订阅