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Disparities in the surgical management of early stage non-small cell lung cancer: how far have we come?

机译:早期非小细胞肺癌手术治疗的差异:我们走了多远?

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摘要

It is currently estimated that nearly one-third of patients with newly diagnosed non-small cell lung cancer (NSCLC) have stage I–II disease on clinical evaluation. Curative-intent surgical resection has been a cornerstone of the therapeutic management of such patients, offering the best clinical and oncologic outcomes in the long-term. In 1999, Peter Bach and colleagues brought attention to racial disparities in the receipt of curative-intent surgery in the NSCLC population. In the time since this seminal study, there is accumulating evidence to suggest that disparities in the receipt of definitive surgery continue to persist for patients with early stage NSCLC. In this review, we sought to provide an up-to-date assessment of 20 years of surgical disparities literature in the NSCLC population. We summarized common and unrecognized disparities in the receipt of surgical resection for early stage NSCLC and demonstrated that demographic and socioeconomic factors such as race/ethnicity, special patient groups, income and insurance continue to impact the receipt of definitive resection. Additionally, we found that discrepancies in patient and provider perceptions of and attitudes toward surgery, access to invasive staging, distance to treatment centers and negative stigmas about lung cancer that patients experience may act to perpetuate disparities in surgical treatment of early stage lung cancer.
机译:目前估计,根据临床评估,近三分之一的新诊断非小细胞肺癌(NSCLC)患者患有I–II期疾病。根治性手术切除已成为此类患者治疗管理的基石,长期而言可提供最佳的临床和肿瘤治疗效果。 1999年,Peter Bach及其同事在NSCLC人群中接受根治性手术的过程中引起了人们对种族差异的关注。自从这项开创性研究以来,有越来越多的证据表明,早期NSCLC患者接受最终手术的差异仍然存在。在这篇综述中,我们试图提供NSCLC人群中20年外科手术差异文献的最新评估。我们总结了早期非小细胞肺癌手术切除接受中的常见和无法识别的差异,并证明了人口统计学和社会经济因素,例如种族/种族,特殊患者群体,收入和保险继续影响最终切除的接受。此外,我们发现患者和医护人员对手术的看法和态度,对侵入性分期的访问,到治疗中心的距离以及患者经历的对肺癌的负面污名上的差异可能会导致早期肺癌的外科治疗中的差异长期存在。

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