Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging

摘要

Objective The purpose of this study was to demonstrate the feasibility of using hyperpolarized carbon-13 (¹³C) metabolic imaging with [1-¹³C]-labeled pyruvate for evaluating real-time in vivo metabolism of orthotopic diffuse intrinsic pontine glioma (DIPG) xenografts.