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Are serum cytokines early predictors for the outcome of burn patients with inhalation injuries who do not survive?

机译:血清细胞因子是否可以作为无法幸存的吸入性烧伤烧伤患者的预后指标?

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摘要

IntroductionSeverely burned patients suffering from inhalation injury have a significantly increased risk for mortality compared with burned patients without inhalation injury. Severe burn is associated with a distinct serum cytokine profile and alterations in cytokines that contribute to morbidity and mortality. The aim of the present study was therefore to determine whether severely burned pediatric patients with concomitant inhalation injury who had a fatal outcome exhibited a different serum cytokine profile compared with burn patients with inhalation injury who survived. Early identification followed by appropriate management of these high-risk patients may lead to improved clinical outcome.
机译:简介与没有吸入伤害的烧伤患者相比,遭受吸入伤害的严重烧伤患者的死亡风险显着增加。严重烧伤与明显的血清细胞因子谱和细胞因子的改变有关,从而导致发病和死亡。因此,本研究的目的是确定与致命存活的烧伤合并吸入性烧伤患者相比,有致命结局的严重烧伤并发吸入性合并烧伤的儿科患者是否表现出不同的血清细胞因子谱。对这些高危患者进行早期鉴定,然后进行适当的管理,可能会改善临床疗效。

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